Controlled Ring-Opening Polymerization of O-Carboxyanhydrides to Synthesize Functionalized Poly(α-Hydroxy Acids)
نویسندگان
چکیده
Poly(α-hydroxy acids), as a family of biodegradable polyesters, are valuable materials due to their broad applications in packaging, agriculture, and biomedical engineering. Herein we highlight explore recent advances catalysts controlled ring-opening polymerization O-carboxyanhydrides towards functionalized poly(α-hydroxy especially metal catalyst-mediated polymerization. Limitations current strategies discussed.
منابع مشابه
Synthesis and biomedical applications of functional poly(α-hydroxy acids) via ring-opening polymerization of O-carboxyanhydrides.
Poly(α-hydroxy acids) (PAHAs) are a class of biodegradable and biocompatible polymers that are widely used in numerous applications. One drawback of these conventional polymers, however, is their lack of side-chain functionalities, which makes it difficult to conjugate active moieties to PAHA or to fine-tune the physical and chemical properties of PAHA-derived materials through side-chain modif...
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متن کاملSynthesis of polypeptides by ring-opening polymerization of α-amino acid N-carboxyanhydrides.
This chapter summarizes methods for the synthesis of polypeptides by ring-opening polymerization. Traditional and recently improved methods used to polymerize α-amino acid N-carboxyanhydrides (NCAs) for the synthesis of homopolypeptides are described. Use of these methods and strategies for the preparation of block copolypeptides and side-chain-functionalized polypeptides are also presented, as...
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ژورنال
عنوان ژورنال: Organic materials
سال: 2021
ISSN: ['2625-1825']
DOI: https://doi.org/10.1055/s-0040-1722698